Set after the collapse of the Earth's ecosystem, VESPER follows the titular headstrong 13-year-old girl (Raffiella Chapman), who uses her survival skills to subsist in the remnants of a strange and dangerous world with her ailing father, Darius (Richard Brake). When Vesper finds a mysterious woman, Camellia (Rosy McEwen), alone and disoriented after an aerial crash, she agrees to help find her missing companion in exchange for safe passage to the Citadel,–the dark central hub where oligarchs live in comfort thanks to state-of-the-art biotechnology. Vesper soon discovers that her brutal neighbor, Jonas (Eddie Marsan), is searching for Camellia, who is harboring a secret that could change all of their lives forever. Forced into a dangerous adventure, Vesper must rely on her wits and bio-hacking abilities to unlock the key to an alternate future.